June: Impact of Social Isolation on Elderly Brain Function

Analyzing cognitive loneliness and its impact on elderly brain function

MONTHLY ISSUES

Joyce Sato, Sri Patel, Aria Fernandes, Evelyn Yao, Sue Nguyen, Hiya Patel

6/30/20251 min read

woman in brown jacket sitting on brown wooden chair
woman in brown jacket sitting on brown wooden chair

Reviewing the Impact of Social isolation on Elderly Brain Function

As people grow older, loneliness and social isolation become more common and begin to affect more than just emotional well-being. Studies now show that isolation can lead to physical changes in the brain, such as reduced hippocampal volume, disrupted default mode network activity, and increased inflammation. These changes are linked to memory loss, depression, and a higher risk of dementia. This paper explores how loneliness impacts brain health through biological, psychological, and social pathways. It examines how social engagement strengthens cognitive function, how culture shapes the way aging and isolation are experienced, and how issues like polypharmacy can worsen mental and neurological decline. By understanding these different factors, we can begin to find better ways to support older adults and protect their cognitive health as they age.